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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK6
All Species:
16.67
Human Site:
T322
Identified Species:
26.19
UniProt:
Q9NQU5
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQU5
NP_001122100.1
681
74869
T322
V
G
T
F
S
P
L
T
T
S
D
T
S
S
P
Chimpanzee
Pan troglodytes
XP_510301
627
67581
V301
L
A
G
E
D
T
G
V
V
T
H
E
Q
F
K
Rhesus Macaque
Macaca mulatta
XP_001093484
681
74821
T322
V
G
T
F
S
P
L
T
T
S
D
T
S
S
P
Dog
Lupus familis
XP_544614
968
105825
T609
M
G
T
F
S
P
L
T
S
Q
D
T
S
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3ULB5
682
74848
T323
M
G
T
F
S
P
L
T
T
S
D
T
S
S
P
Rat
Rattus norvegicus
Q62829
544
60692
K218
A
S
P
A
A
P
N
K
E
A
T
P
P
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515215
639
68748
G313
P
G
R
P
S
P
A
G
S
P
R
T
R
P
A
Chicken
Gallus gallus
XP_426393
667
74767
A322
T
P
Q
R
S
P
T
A
E
K
A
I
A
V
P
Frog
Xenopus laevis
NP_001082100
650
73749
K317
Q
Q
G
Q
V
K
P
K
P
P
E
K
P
H
P
Zebra Danio
Brachydanio rerio
XP_001919719
693
77347
S322
R
H
Q
A
S
V
R
S
S
C
S
Y
T
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VXE5
639
69601
S313
Q
H
L
A
K
S
A
S
R
A
S
S
S
S
G
Honey Bee
Apis mellifera
XP_001122147
624
70155
N298
L
S
Q
L
S
T
H
N
V
N
K
Y
S
Q
S
Nematode Worm
Caenorhab. elegans
Q17850
572
63863
K246
L
S
I
Y
T
K
P
K
E
E
E
E
K
I
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q03497
939
102344
S473
A
N
G
K
F
I
P
S
R
P
A
P
K
P
P
Red Bread Mold
Neurospora crassa
Q7RZD3
954
103773
G471
A
P
P
P
V
P
K
G
P
G
P
L
P
A
K
Conservation
Percent
Protein Identity:
100
52.7
98.5
66.4
N.A.
92.5
30.6
N.A.
62.2
75.9
46.7
52.5
N.A.
44.3
44.9
29.8
N.A.
Protein Similarity:
100
60.7
98.9
67.6
N.A.
95.5
48.4
N.A.
69.9
82.3
61.6
64.5
N.A.
57.5
57.5
47.2
N.A.
P-Site Identity:
100
0
100
80
N.A.
93.3
13.3
N.A.
26.6
20
6.6
6.6
N.A.
13.3
13.3
6.6
N.A.
P-Site Similarity:
100
13.3
100
93.3
N.A.
100
26.6
N.A.
33.3
26.6
13.3
26.6
N.A.
33.3
26.6
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.5
28
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43.1
41.6
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
7
0
20
7
0
14
7
0
14
14
0
7
7
14
% A
% Cys:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
0
0
0
27
0
0
0
0
% D
% Glu:
0
0
0
7
0
0
0
0
20
7
14
14
0
0
0
% E
% Phe:
0
0
0
27
7
0
0
0
0
0
0
0
0
7
0
% F
% Gly:
0
34
20
0
0
0
7
14
0
7
0
0
0
0
14
% G
% His:
0
14
0
0
0
0
7
0
0
0
7
0
0
7
0
% H
% Ile:
0
0
7
0
0
7
0
0
0
0
0
7
0
7
0
% I
% Lys:
0
0
0
7
7
14
7
20
0
7
7
7
14
0
14
% K
% Leu:
20
0
7
7
0
0
27
0
0
0
0
7
0
7
0
% L
% Met:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
7
7
0
7
0
0
0
0
0
% N
% Pro:
7
14
14
14
0
54
20
0
14
20
7
14
20
14
54
% P
% Gln:
14
7
20
7
0
0
0
0
0
7
0
0
7
7
0
% Q
% Arg:
7
0
7
7
0
0
7
0
14
0
7
0
7
0
0
% R
% Ser:
0
20
0
0
54
7
0
20
20
20
14
7
40
40
7
% S
% Thr:
7
0
27
0
7
14
7
27
20
7
7
34
7
0
0
% T
% Val:
14
0
0
0
14
7
0
7
14
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
14
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _